Peptide Name: Kaliotoxin
Structuire: (Disulfide bonds between Cys8 and Cys28/Cys14 and Cys33/ Cys18 and Cys35)GVEINVKCSGSPQCLKPCKDAGMRFGKCMNRKCHCTPK
M.W. 4150.01
Notes: High conductance Calcium activated K+ channel blocker. Kaliotoxin, originally purified from the venom of the scorpion Androctonus mauretanicus mauretanicus, is a 38amino acid peptide showing 44% sequence homology with charybdotoxin and iberiotoxin. It acts as a specific, voltage-independent inhibitor of high conductance Ca2+ activated K+ channels present in mollusc and rabbit nerve cells.
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